There’s nothing spare about that tire sitting above your hips. No emergency in the world would make it necessary to carry around. Some women are plagued by a fluffy gut, even when they eat right and exercise like nobody’s business. Genetics plays a role in weight gain for some. For others, it’s attributed to out-of-sync hormones. Women with PCOS struggle with unwanted pounds that are hard to shed. Berberine supplements can help whittle that waist by supporting glucose metabolism. When paired with a healthy eating plan and daily exercise routine, kicking that tire to the curb is a realistic goal.